ToxProbe Today

Environmental, Occupational Health & Risk Assessment News Sept 2002 (Vol. 1- 9)


 

Legislation/Regulation

Health Canada and the Canadian Food Inspection Agency (CFIA) have released a new discussion paper on developing revised federal regulations concerning bottled water and prepackaged ice. Making it Clear - Renewing the Federal Regulations on Bottled Water: A Discussion Paper is now available at http://www.hc-sc.gc.ca/food-aliment/friia-raaii/frp-pra/water-eau/e_rfr_bottle_water_tofc.php. Responses to the proposal will be accepted until November 30, 2002.

Publications

Environment Canada recently published the results of investigations and recommendations for substances pursuant to the Canadian Environmental Protection Act, 1999 (Canada Gazette, Part I, Sept. 28, 2002). The specific substances are di-n-octyl phthalate, styrene, 1,1,2,2-tetrachloroethane, 1,2-dichlorobenzene, 1,4-dichlorobenzene, trichlorobenzenes, tetrachlorobenzenes and pentachlorobenzene. The deadline date for public comment on the reports is November 27, 2002.

Toxic Chemicals Update (Environment Canada Atlantic Region, Vol. 5, Issue 1, 2002). Highlights of the latest newsletter include a discussion of the Stephenville, Newfoundland risk assessment and chemical spill contingency planning. The newsletter is be found at http://www.ns.ec.gc.ca/epb/newsletters/toxchem/toxic_chem8.html

11th Biennial Report: Great Lakes Water Quality (International Joint Commission, 2002). One of the findings of the report is that a convincing body of scientific research shows that toxic substances accumulate in humans who eat certain Great Lakes fish, and that this exposure can cause serious injury to health. http://www.ijc.org/ijcweb-e.html

Environmental Health

The South Coast Air Quality Management District in California has proposed to phase out perchloroethylene (the most commonly used dry cleaning solvent) on the grounds that it endangers public health. The district's board is expected to vote as early as November 1. If the measure passes, the use of perchloroethylene would be phased out by 2019. Among the toxic substances in the Los Angeles region's air, perchloroethylene is estimated to cause more cases of cancer than anything except diesel exhaust, according to a 2000 air district study.

Technical Guidelines

The U.S. EPA, in conjunction with other partners, has developed a no-cost, online Persistent, Bio-accumulative, Toxic (PBT) screening methodology. The methodology, called "PBT Profiler", was designed to be an easy to use, widely available, no-cost tool to screen chemicals lacking experimental data in order to help identify pollution prevention (P2) opportunities. It is a continuation of the U.S. EPA P2 Assessment Framework - a collection of screening models and methods to help promote the design, development, and application of safer chemicals and processes. The P2 Framework uses computerized methods, such as structure/activity relationships (SARs) and standard scenarios, to predict risk related data on chemicals lacking experimental data. The PBT Profiler is available at http://esc.syrres.com/pbt/ - soon to be www.pbtprofiler.net.

Research & Development

The U.S. EPA National Center for Environmental Assessment recently released a report that concluded diesel exhaust from large trucks and other sources probably cause lung cancer. While noting that there are still uncertainties about the long term effects of exposure to diesel exhaust, the report warns that chronic inhalation of the fumes at levels now present in many urban environments "is likely to pose a lung cancer hazard to humans, as well as damage the lung in other ways depending on exposure."

A recently released study analyzed population-based childhood cancer incidence rates throughout California in relation to agricultural pesticide use. Building on the availability of population-based cancer incidence information, the authors used a geographic information system to assign summary population, exposure, and outcome attributes at the block group level. The authors generally found no association between pesticide use density and childhood cancer incidence rates. Although follow-up studies that can better address timing of exposure will be important in assessing the etiologic significance of pesticide exposures, this study does address the public concern about whether rates of childhood cancer are higher in areas of heavy agricultural pesticide use. The observed lack of association in this study stands in contrast to evidence on household use from the case-control literature, but does not necessarily imply a lack of association with pesticide exposures in general. The current study focuses on residence in areas of high agricultural pesticide use. Environ Health Perspective 110:319-324(2002).

Risk Trivia

How many time as likely is it for whites to die from the following causes than blacks (e.g. 3 to 1)?

1. Suicide.
2. Mental disorders (among women).
3. Falling (among women).
4. Coronary heart disease.
5. Water transport accidents (among men).

Answers will be provided in next month's issue of ToxProbe Today.

Answer: August 2002 Risk Trivia

How many time as likely is it for blacks to die from the following causes than whites (e.g. 3 to 1)?

1. Cerebrovascular disease.
2. Diabetes.
3. Appendicitis.
4. Hypertensive heart disease.
5. Whooping cough.

Answers:

1. 2 to 1.
2. 2 to 1.
3. 3 to 1.
4. 5 to 1.
5. 6 to 1.